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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNM1L All Species: 44.85
Human Site: S39 Identified Species: 70.48
UniProt: O00429 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00429 NP_005681.2 736 81877 S39 G T Q S S G K S S V L E S L V
Chimpanzee Pan troglodytes XP_520720 896 98575 G92 G T Q V R A A G G V R S G Q T
Rhesus Macaque Macaca mulatta XP_001086126 725 80517 S39 G T Q S S G K S S V L E S L V
Dog Lupus familis XP_864886 736 81869 S39 G T Q S S G K S S V L E S L V
Cat Felis silvestris
Mouse Mus musculus Q8K1M6 742 82640 S39 G T Q S S G K S S V L E S L V
Rat Rattus norvegicus O35303 755 83890 S39 G T Q S S G K S S V L E S L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073190 696 77727 S39 G T Q S S G K S S V L E S L V
Frog Xenopus laevis NP_001080183 698 77807 S39 G T Q S S G K S S V L E S L V
Zebra Danio Brachydanio rerio Q7SXN5 691 77244 S39 G T Q S S G K S S V L E S L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27619 877 97791 G33 L P Q I A V V G G Q S A G K S
Honey Bee Apis mellifera XP_394947 721 81070 S39 G T Q S S G K S S V I E S L V
Nematode Worm Caenorhab. elegans P39055 830 93389 F31 Q L G T S V S F E L P Q I A V
Sea Urchin Strong. purpuratus XP_802061 717 80361 S39 G N Q S S G K S S V L E G L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LFT2 780 86625 Q52 Q V A V V G S Q S S G K S S V
Baker's Yeast Sacchar. cerevisiae P54861 757 84953 S42 G S Q S S G K S S I L E T L V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.5 98.5 99.1 N.A. 97.8 96.4 N.A. N.A. 89.8 87 86 N.A. 33.9 66.8 35.6 68.7
Protein Similarity: 100 79.9 98.5 99.5 N.A. 98.3 97.2 N.A. N.A. 91.8 90.9 90.3 N.A. 52.2 79.7 53.9 82.2
P-Site Identity: 100 26.6 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 6.6 93.3 13.3 86.6
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 13.3 100 33.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. 42.4 45.5 N.A.
Protein Similarity: N.A. N.A. N.A. 59.4 65.2 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 80 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 7 7 0 0 0 0 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 0 0 74 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 80 0 7 0 0 80 0 14 14 0 7 0 20 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 7 7 0 7 0 0 % I
% Lys: 0 0 0 0 0 0 74 0 0 0 0 7 0 7 0 % K
% Leu: 7 7 0 0 0 0 0 0 0 7 67 0 0 74 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % P
% Gln: 14 0 87 0 0 0 0 7 0 7 0 7 0 7 0 % Q
% Arg: 0 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % R
% Ser: 0 7 0 74 80 0 14 74 80 7 7 7 67 7 7 % S
% Thr: 0 67 0 7 0 0 0 0 0 0 0 0 7 0 7 % T
% Val: 0 7 0 14 7 14 7 0 0 74 0 0 0 0 87 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _